Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
In Sequential Viterbi Models, such as HMMs, MEMMs, and Linear Chain CRFs, the type of patterns over output sequences that can be learned by the model depend directly on the modelâ...
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...