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BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
BMCBI
2004
265views more  BMCBI 2004»
13 years 7 months ago
ASAView: Database and tool for solvent accessibility representation in proteins
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...
Shandar Ahmad, M. Michael Gromiha, Hamed Fawareh, ...
LION
2009
Springer
135views Optimization» more  LION 2009»
14 years 2 months ago
Neural Network Pairwise Interaction Fields for Protein Model Quality Assessment
We present a new knowledge-based Model Quality Assessment Program (MQAP) at the residue level which evaluates single protein structure models. We use a tree representation of the ...
Alberto J. M. Martin, Alessandro Vullo, Gianluca P...
BMCBI
2007
165views more  BMCBI 2007»
13 years 7 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio