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BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
BIBM
2007
IEEE
104views Bioinformatics» more  BIBM 2007»
13 years 11 months ago
A Protocol to Detect Local Affinities Involved in Proteins Distant Interactions
The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
Christophe Nicolas Magnan, Cécile Capponi, ...
RECOMB
2005
Springer
14 years 7 months ago
Segmentation Conditional Random Fields (SCRFs): A New Approach for Protein Fold Recognition
Abstract. Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e. segmenta...
Yan Liu, Jaime G. Carbonell, Peter Weigele, Vanath...
RECOMB
2006
Springer
14 years 7 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
BMCBI
2008
200views more  BMCBI 2008»
13 years 7 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia