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BMCBI
2007
182views more  BMCBI 2007»
13 years 7 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
BMCBI
2005
130views more  BMCBI 2005»
13 years 7 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
GCB
2005
Springer
98views Biometrics» more  GCB 2005»
14 years 27 days ago
Composite Module Analyst: A Fitness-Based Tool for Prediction of Transcription Regulation
: Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely...
Alexander E. Kel, Tatiana Konovalova, Tagir Valeev...
BMCBI
2007
136views more  BMCBI 2007»
13 years 7 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette