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IEEEICCI
2006
IEEE
14 years 1 months ago
Using Feature Selection Filtering Methods for Binding Site Predictions
Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. In previous work we applied classification techniques on predictio...
Yi Sun, Mark Robinson, Rod Adams, Rene te Boekhors...
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
NAR
2010
107views more  NAR 2010»
13 years 2 months ago
FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
FlyTF (http://www.flytf.org) is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melano...
Ulrike Pfreundt, Daniel P. James, Susan Tweedie, D...
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
TCS
2008
13 years 7 months ago
Detection of subtle variations as consensus motifs
We address the problem of detecting consensus motifs, that occur with subtle variations, across multiple sequences. These are usually functional domains in DNA sequences such as t...
Matteo Comin, Laxmi Parida