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COR
2008
122views more  COR 2008»
13 years 9 months ago
First steps to the runtime complexity analysis of ant colony optimization
: The paper presents results on the runtime complexity of two ant colony optimization (ACO) algorithms: Ant System, the oldest ACO variant, and GBAS, the first ACO variant for whic...
Walter J. Gutjahr
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 9 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
202views more  BMCBI 2006»
13 years 9 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
BMCBI
2007
138views more  BMCBI 2007»
13 years 9 months ago
A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
Background: A key challenge in metabonomics is to uncover quantitative associations between multidimensional spectroscopic data and biochemical measures used for disease risk asse...
Aki Vehtari, Ville-Petteri Mäkinen, Pasi Soin...
BMCBI
2007
217views more  BMCBI 2007»
13 years 9 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin