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BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
ICASSP
2007
IEEE
14 years 2 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
EC
2007
160views ECommerce» more  EC 2007»
13 years 7 months ago
Agent-Based Model of Genotype Editing
Evolutionary algorithms rarely deal with ontogenetic, non-inherited alteration of genetic information because they are based on a direct genotype-phenotype mapping. In contrast, i...
Chien-Feng Huang, Jasleen Kaur, Ana Gabriela Magui...
RECOMB
2010
Springer
14 years 2 months ago
Genomic DNA k-mer Spectra: Models and Modalities
Background: The empirical frequencies of DNA k-mers in whole genome sequences provide an interesting perspective on genomic complexity, and the availability of large segments of g...
Benny Chor, David Horn, Nick Goldman, Yaron Levy, ...
HICSS
2003
IEEE
151views Biometrics» more  HICSS 2003»
14 years 1 months ago
A Simple GSPN for Modeling Common Mode Failures in Critical Infrastructures
It is now apparent that our nation’s infrastructures and essential utilities have been optimized for reliability in benign operating environments. As such, they are susceptible ...
Axel W. Krings, Paul W. Oman