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BMCBI
2007
123views more  BMCBI 2007»
15 years 4 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BMCBI
2007
182views more  BMCBI 2007»
15 years 4 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2004
185views more  BMCBI 2004»
15 years 4 months ago
Linear fuzzy gene network models obtained from microarray data by exhaustive search
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
Bahrad A. Sokhansanj, J. Patrick Fitch, Judy N. Qu...
GECCO
2009
Springer
131views Optimization» more  GECCO 2009»
15 years 1 months ago
A multi-objective approach to data sharing with privacy constraints and preference based objectives
Public data sharing is utilized in a number of businesses to facilitate the exchange of information. Privacy constraints are usually enforced to prevent unwanted inference of info...
Rinku Dewri, Darrell Whitley, Indrajit Ray, Indrak...
GECCO
2007
Springer
163views Optimization» more  GECCO 2007»
15 years 10 months ago
Exploring medical data using visual spaces with genetic programming and implicit functional mappings
Two medical data sets (Breast cancer and Colon cancer) are investigated within a visual data mining paradigm through the unsupervised construction of virtual reality spaces using ...
Julio J. Valdés, Robert Orchard, Alan J. Ba...