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JMLR
2012
11 years 11 months ago
Active Clustering of Biological Sequences
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...
CSB
2004
IEEE
142views Bioinformatics» more  CSB 2004»
14 years 10 days ago
FastR: Fast Database Search Tool for Non-Coding RNA
The discovery of novel non-coding RNAs has been among the most exciting recent developments in Biology. Yet, many more remain undiscovered. It has been hypothesized that there is ...
Vineet Bafna, Shaojie Zhang
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 6 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
NAR
2006
134views more  NAR 2006»
13 years 8 months ago
The MPI Bioinformatics Toolkit for protein sequence analysis
The MPI Bioinformatics Toolkit is an interactive web service which offers access to a great variety of public and in-house bioinformatics tools. They are grouped into different se...
Andreas Biegert, Christian Mayer, Michael Remmert,...
BMCBI
2008
200views more  BMCBI 2008»
13 years 8 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia