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BMCBI
2006
126views more  BMCBI 2006»
13 years 7 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2007
154views more  BMCBI 2007»
13 years 7 months ago
Inferring biological networks with output kernel trees
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
BMCBI
2007
215views more  BMCBI 2007»
13 years 7 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
CORRIE: enzyme sequence annotation with confidence estimates
Using a previously developed automated method for enzyme annotation, we report the reannotation of the ENZYME database and the analysis of local error rates per class. In control ...
Benjamin Audit, Emmanuel D. Levy, Walter R. Gilks,...