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BMCBI
2010
13 years 7 months ago
2010
Background: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the num...
BMCBI
2008
13 years 7 months ago
2008
Background: The traditional (unweighted) k-means is one of the most popular clustering methods for analyzing gene expression data. However, it suffers three major shortcomings. It...
BMCBI
2010
13 years 7 months ago
2010
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
BMCBI
2008
13 years 7 months ago
2008
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
BMCBI
2007
13 years 7 months ago
2007
Background: Novel molecular and statistical methods are in rising demand for disease diagnosis and prognosis with the help of recent advanced biotechnology. High-resolution mass s...