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» Problems on RNA Secondary Structure Prediction and Design
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BMCBI
2006
161views more  BMCBI 2006»
13 years 8 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
BMCBI
2005
162views more  BMCBI 2005»
13 years 8 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
RECOMB
2006
Springer
14 years 9 months ago
Structural Alignment of Pseudoknotted RNA
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
Banu Dost, Buhm Han, Shaojie Zhang, Vineet Bafna
ICPP
2006
IEEE
14 years 2 months ago
A Parallel, Out-of-Core Algorithm for RNA Secondary Structure Prediction
RNA pseudoknot prediction is an algorithm for RNA sequence search and alignment. An important building block towards pseudoknot prediction is RNA secondary structure prediction. T...
Wenduo Zhou, David K. Lowenthal
BIBM
2008
IEEE
105views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Energy Profile and Secondary Structure Impact shRNA Efficacy
Many characteristics of functional synthetic siRNAs have been identified. Our three-phase algorithm was developed to design siRNA on a wholegenome scale based on these characteris...
Hong Zhou, Xiao Zeng