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BMCBI
2010
104views more  BMCBI 2010»
13 years 10 months ago
Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...
Anil Sorathiya, Andrea Bracciali, Pietro Liò...
BMCBI
2008
164views more  BMCBI 2008»
13 years 10 months ago
MeInfoText: associated gene methylation and cancer information from text mining
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
Yu-Ching Fang, Hsuan-Cheng Huang, Hsueh-Fen Juan
BMCBI
2010
175views more  BMCBI 2010»
13 years 10 months ago
Global parameter estimation methods for stochastic biochemical systems
Background: The importance of stochasticity in cellular processes having low number of molecules has resulted in the development of stochastic models such as chemical master equat...
Suresh Kumar Poovathingal, Rudiyanto Gunawan
BMCBI
2007
151views more  BMCBI 2007»
13 years 10 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
BMCBI
2007
109views more  BMCBI 2007»
13 years 10 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat