Building the semantic web encounters problems similar to building large bibliographic systems. The experience of librarianship in controlling large, heterogeneous collections of b...
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
it’s hardly Earth-shattering: abstracting your business services and separating them from your applications can yield an overall system that’s easier to build, maintain, and ex...
1 The latent semantic indexing (LSI) methodology for information retrieval applies the singular value decomposition to identify an eigensystem for a large matrix, in which cells re...
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...