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BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
BMCBI
2010
102views more  BMCBI 2010»
13 years 8 months ago
SAMPLEX: Automatic mapping of perturbed and unperturbed regions of proteins and complexes
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Mickaël Krzeminski, Karine Loth, Rolf Boelens...
BMCBI
2010
155views more  BMCBI 2010»
13 years 8 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
BMCBI
2006
102views more  BMCBI 2006»
13 years 8 months ago
SNA - a toolbox for the stoichiometric analysis of metabolic networks
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
Robert Urbanczik
BMCBI
2007
124views more  BMCBI 2007»
13 years 8 months ago
Protein structural similarity search by Ramachandran codes
Background: Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed...
Wei-Cheng Lo, Po-Jung Huang, Chih-Hung Chang, Ping...