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BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
CrossHybDetector: detection of cross-hybridization events in DNA microarray experiments
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
Paolo Uva, Emanuele de Rinaldis
BIB
2006
169views more  BIB 2006»
13 years 7 months ago
Bio-ontologies: current trends and future directions
: In recent years, as a knowledge-based discipline, bioinformatics has moved to make its knowledge more computationally amenable. After its beginnings in the disciplines as a techn...
Olivier Bodenreider, Robert Stevens
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
JLIN: A java based linkage disequilibrium plotter
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Cell_motility: a cross-platform, open source application for the study of cell motion paths
Background: Migration is an important aspect of cellular behaviour and is therefore widely studied in cell biology. Numerous components are known to participate in this process in...
Lennart Martens, Geert Monsieur, Christophe Ampe, ...