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LFP
1992
140views more  LFP 1992»
15 years 7 months ago
Global Tagging Optimization by Type Inference
Tag handling accounts for a substantial amount of execution cost in latently typed languages such as Common LISP and Scheme, especially on architectures that provide no special ha...
Fritz Henglein
BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-or
Background: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to ...
Eelke van der Horst, Julio E. Peironcely, Adriaan ...
BMCBI
2007
127views more  BMCBI 2007»
15 years 6 months ago
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
BMCBI
2007
121views more  BMCBI 2007»
15 years 6 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
BMCBI
2010
139views more  BMCBI 2010»
15 years 6 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
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