Background: Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many pr...
Joan Teyra, Maciej Paszkowski-Rogacz, Gerd Anders,...
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...
This paper presents the Architecture Tradeoff Analysis Method (ATAM), a structured technique for understanding the tradeoffs inherent in design. This method was developed to provi...
Rick Kazman, Mark H. Klein, Mario Barbacci, Thomas...
Despite the potential of domain ontologies to provide consensual representations of domain-relevant knowledge, the open, distributed and decentralized nature of the Semantic Web me...
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...