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» ProtRepeatsDB: a database of amino acid repeats in genomes
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BMCBI
2004
154views more  BMCBI 2004»
13 years 7 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2007
167views more  BMCBI 2007»
13 years 7 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
NAR
1998
70views more  NAR 1998»
13 years 7 months ago
Haemophilia B: database of point mutations and short additions and deletions--eighth edition
The eighth edition of the haemophilia B database (http://www.umds.ac.uk/molgen/haemBdatabase.htm ) lists in an easily accessible form all known factor IX mutations due to small ch...
F. Giannelli, P. M. Green, S. S. Sommer, M.-C. Poo...
GCB
2004
Springer
223views Biometrics» more  GCB 2004»
13 years 11 months ago
PoSSuMsearch: Fast and Sensitive Matching of Position Specific Scoring Matrices using Enhanced Suffix Arrays
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
Michael Beckstette, Dirk Strothmann, Robert Homann...