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BMCBI
2008
110views more  BMCBI 2008»
13 years 7 months ago
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated da
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
Optimised amino acid specific weighting factors for unbound protein docking
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
Philipp Heuser, Dietmar Schomburg
CANPC
1999
Springer
13 years 12 months ago
Implementing Application-Specific Cache-Coherence Protocols in Configurable Hardware
Streamlining communication is key to achieving good performance in shared-memory parallel programs. While full hardware support for cache coherence generally offers the best perfo...
David Brooks, Margaret Martonosi
JSW
2008
101views more  JSW 2008»
13 years 7 months ago
Graphical Mission Specification and Partitioning for Unmanned Underwater Vehicles
- The use of Unmanned Underwater Vehicles (UUVs) has been proposed for several different types of applications including hydrographic surveys (e.g., mapping the ocean floor and exp...
Gary Giger, Mahmut T. Kandemir, John Dzielski
BMCBI
2005
141views more  BMCBI 2005»
13 years 7 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...