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BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Projections for fast protein structure retrieval
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
JOI
2007
99views more  JOI 2007»
13 years 7 months ago
Measuring quality of similarity functions in approximate data matching
This paper presents a method for assessing the quality of similarity functions. The scenario taken into account is that of approximate data matching, in which it is necessary to d...
Roberto da Silva, Raquel Kolitski Stasiu, Viviane ...
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 5 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...