194 search results - page 6 / 39 » Protein Design by Optimization of a Sequence-Structure Quali... |
GECCO
2000
Springer
13 years 11 months ago
2000
Springer
We present a new representation for a genetic algorithm to evolve molecular structures representing possible drugs that bind to a given protein target receptor. Our representation...
IPPS
2006
IEEE
14 years 1 months ago
2006
IEEE
The prediction of protein 3D structure has become a hot research area in the post-genome era, through which people can understand a protein’s function in health and disease, exp...
BMCBI
2010
13 years 7 months ago
2010
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
BMCBI
2007
13 years 7 months ago
2007
Background: Many algorithms exist for protein structural alignment, based on internal protein coordinates or on explicit superposition of the structures. These methods are usually...
GECCO
2005
Springer
14 years 1 months ago
2005
Springer
The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...