194 search results - page 7 / 39 » Protein Design by Optimization of a Sequence-Structure Quali... |
RECOMB
2012
Springer
11 years 11 months ago
2012
Springer
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
ECRTS
2002
IEEE
2002
IEEE
Managing Multi-Mode Tasks with Time Cost and Quality Levels using Optimal Discrete Control Synthesis
14 years 1 months ago
Real-time control systems are complex to design, and automation support is important. We are interested in systems with multiple tasks, each with multiple modes, implementing a fu...
BMCBI
2010
13 years 9 months ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
BMCBI
2006
13 years 8 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
BMCBI
2006
13 years 8 months ago
2006
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...