Fold recognition is a key problem in computational biology that involves classifying protein sharing structural similarities into classes commonly known as "folds". Rece...
We develop a novel multi-class classification method based on output codes for the problem of classifying a sequence of amino acids into one of many known protein structural class...
Eugene Ie, Jason Weston, William Stafford Noble, C...
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
Abstract. In this paper, dimensionality reduction via matrix factorization with nonnegativity constraints is studied. Because of these constraints, it stands apart from other linea...