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» Protein Model Representation and Construction
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BMCBI
2005
137views more  BMCBI 2005»
13 years 8 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
BMCBI
2007
113views more  BMCBI 2007»
13 years 8 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...
BIOSYSTEMS
2008
83views more  BIOSYSTEMS 2008»
13 years 8 months ago
Hydrophobic condensation and modular assembly model of protein folding
Despite several decades of intense study, protein folding problem remains elusive. In this paper, we review current knowledge and the prevailing thinking in the field, and summari...
Tian-Yow Tsong, Chin-Kun Hu, Ming-Chya Wu
ATAL
2007
Springer
14 years 18 days ago
On discovery and learning of models with predictive representations of state for agents with continuous actions and observations
Models of agent-environment interaction that use predictive state representations (PSRs) have mainly focused on the case of discrete observations and actions. The theory of discre...
David Wingate, Satinder P. Singh
BMCBI
2010
154views more  BMCBI 2010»
13 years 8 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin