Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
An important problem in high-throughput protein crystallography is constructing a protein model from an electron-density map. Previous work by some of this paper’s authors [1] d...
Frank DiMaio, Ameet Soni, George N. Phillips, Jude...
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
Knowledge models are structured representations of knowledge using symbols to represent pieces of knowledge and relationships between them, while a knowledge building community inv...
The term “changes in structure,” originating from work in econometrics, refers to structural modifications invoked by actions on a causal model. In this paper we formalize the...