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» Protein Model Representation and Construction
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BMCBI
2006
143views more  BMCBI 2006»
15 years 5 months ago
Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
Eric D. Scheeff, Philip E. Bourne
BIBM
2007
IEEE
101views Bioinformatics» more  BIBM 2007»
15 years 12 months ago
Improved Methods for Template-Matching in Electron-Density Maps Using Spherical Harmonics
An important problem in high-throughput protein crystallography is constructing a protein model from an electron-density map. Previous work by some of this paper’s authors [1] d...
Frank DiMaio, Ameet Soni, George N. Phillips, Jude...
BMCBI
2007
135views more  BMCBI 2007»
15 years 5 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
ITRE
2006
IEEE
15 years 11 months ago
A Knowledge Building Community Constructing a Knowledge Model Using Online Concept Maps
Knowledge models are structured representations of knowledge using symbols to represent pieces of knowledge and relationships between them, while a knowledge building community inv...
Moshe Leiba, Rafi Nachmias
ECSQARU
2001
Springer
15 years 10 months ago
Supporting Changes in Structure in Causal Model Construction
The term “changes in structure,” originating from work in econometrics, refers to structural modifications invoked by actions on a causal model. In this paper we formalize the...
Tsai-Ching Lu, Marek J. Druzdzel