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» Protein contact order prediction from primary sequences
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BMCBI
2007
117views more  BMCBI 2007»
13 years 7 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
13 years 7 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
CSB
2005
IEEE
143views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Analysis of four different sets of predictive features for metalloproteins
Metals bound to the protein are important for functional or structural roles. Despite their importance there is a distinct lack of research for identification of metalloproteins f...
Huseyin Seker, Parvez I. Haris
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary informa
Background: In past number of methods have been developed for predicting subcellular location of eukaryotic, prokaryotic (Gram-negative and Gram-positive bacteria) and human prote...
Mamoon Rashid, Sudipto Saha, Gajendra P. S. Raghav...
BMCBI
2008
75views more  BMCBI 2008»
13 years 7 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...