50 search results - page 4 / 10 » Protein homology detection using string alignment kernels |
139
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
167
Voted
BMCBI
2011
14 years 10 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
172
Voted
WABI
2009
Springer
15 years 10 months ago
2009
Springer
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
138
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
118
Voted
BIOINFORMATICS
2005
15 years 3 months ago
2005
A key issue in supervised protein classification is the representation of input sequences of amino acids. Recent work using string kernels for protein data has achieved state-of-t...