Understanding the relationship between protein structure and its sequence is one of the most important tasks of current bioinformatics research. In this work, recurring protein se...
Wei Zhong, Gulsah Altun, Robert W. Harrison, Phang...
-We demonstrate a new algorithm named FlexStem to predict RNA secondary structures with pseudoknots. Our approach is based on the free energy minimization criterion, and utilizes a...
Xiang Chen, Simin He, Dongbo Bu, Runsheng Chen, We...
Local search (LS) algorithms are among the most powerful techniques for solving computationally hard problems in combinatorial optimization. These algorithms could be viewed as &q...
We have developed a novel algorithm for protein backbone structure determination using global orientational restraints on internuclear bond vectors derived from residual dipolar c...
Lincong Wang, Ramgopal R. Mettu, Ryan H. Lilien, B...
Genetic Algorithms (GAs), as nondeterministic conformational search techniques, are promising for solving protein structure prediction (PSP) problems. The crossover operator of a ...
Tamjidul Hoque, Madhu Chetty, Andrew Lewis, Abdul ...