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» Proteome analysis based on motif statistics
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BMCBI
2006
95views more  BMCBI 2006»
13 years 7 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
BMCBI
2007
247views more  BMCBI 2007»
13 years 7 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
BMCBI
2007
83views more  BMCBI 2007»
13 years 7 months ago
Identification of sequence motifs significantly associated with antisense activity
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Kyle A. McQuisten, Andrew S. Peek
DILS
2007
Springer
13 years 9 months ago
A High-Throughput Bioinformatics Platform for Mass Spectrometry-Based Proteomics
The success of mass spectrometry-based proteomics in emerging applications such as biomarker discovery and clinical diagnostics, is predicated substantially on its ability to achie...
Thodoros Topaloglou, Moyez Dharsee, Rob M. Ewing, ...
BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
2DDB - a bioinformatics solution for analysis of quantitative proteomics data
Background: We present 2DDB, a bioinformatics solution for storage, integration and analysis of quantitative proteomics data. As the data complexity and the rate with which it is ...
Lars Malmström, György Marko-Varga, Guni...