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    BMCBI
    2010
    88views more  BMCBI 2010»
    Proteome scanning to predict PDZ domain interactions using support vector machines
    13 years 11 months ago
    Proteome scanning to predict PDZ domain interactions using support vector machines
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    Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
    Shirley Hui, Gary D. Bader
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    BMCBI
    2010
    159views more  BMCBI 2010»
    Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
    13 years 11 months ago
    Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
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    Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
    Alvaro J. González, Li Liao
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    BMCBI
    2008
    134views more  BMCBI 2008»
    Prediction of protein-protein binding site by using core interface residue and support vector machine
    13 years 11 months ago
    Prediction of protein-protein binding site by using core interface residue and support vector machine
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    Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
    Nan Li, Zhonghua Sun, Fan Jiang
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    BIBE
    2007
    IEEE
    142views Bioinformatics» more  BIBE 2007»
    An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
    14 years 5 months ago
    An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
    Download  www1.i2r.a-star.edu.sg
    —Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...
    Xiaoli Li, Jun-Xiang Lee, Bharadwaj Veeravalli, Se...
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    BMCBI
    2004
    123views more  BMCBI 2004»
    Interaction profile-based protein classification of death domain
    13 years 11 months ago
    Interaction profile-based protein classification of death domain
    Download  cbio.ensmp.fr
    Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
    Drew Lett, Michael Hsing, Frederic Pio
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