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BMCBI
2010
154views more  BMCBI 2010»
13 years 9 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2008
87views more  BMCBI 2008»
13 years 9 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
CCR
2008
109views more  CCR 2008»
13 years 9 months ago
An independent H-TCP implementation under FreeBSD 7.0: description and observed behaviour
A key requirement for IETF recognition of new TCP algorithms is having an independent, interoperable implementation. This paper describes our BSD-licensed implementation of H-TCP ...
Grenville J. Armitage, Lawrence Stewart, Michael W...
BMCBI
2007
101views more  BMCBI 2007»
13 years 9 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
BMCBI
2011
13 years 4 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder