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BMCBI
2007
118views more  BMCBI 2007»
13 years 10 months ago
A topological algorithm for identification of structural domains of proteins
Background: Identification of the structural domains of proteins is important for our understanding of the organizational principles and mechanisms of protein folding, and for ins...
Frank Emmert-Streib, Arcady R. Mushegian
BMCBI
2007
113views more  BMCBI 2007»
13 years 10 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
ACS
2006
13 years 10 months ago
Universality of Coproducts in Categories of Lax Algebras
Abstract. Categories of lax (T, V )-algebras are shown to have pullbackstable coproducts if T preserves inverse images. The general result not only gives a common proof of this pro...
Mojgan Mahmoudi, Christoph Schubert, Walter Tholen
BMCBI
2006
180views more  BMCBI 2006»
13 years 10 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2006
128views more  BMCBI 2006»
13 years 10 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...