Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
This workfocuses on the inference of evolutionary relationships in protein superfamilies, and the uses of these relationships to identify keypositions in the structure, to infer a...
Background: Phylogenetic trees are an important tool for representing evolutionary relationships among organisms. In a phylogram or chronogram, the ordering of taxa is not conside...
Francesco Cerutti, Luigi Bertolotti, Tony L. Goldb...
Abstract. Given a distance matrix M that specifies the pairwise evolutionary distances between n species, the phylogenetic tree reconstruction problem asks for an edge-weighted ph...
Ho-Leung Chan, Jesper Jansson, Tak Wah Lam, Siu-Mi...