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» QNet: A Tool for Querying Protein Interaction Networks
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BMCBI
2010
102views more  BMCBI 2010»
13 years 2 months ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
BMCBI
2010
177views more  BMCBI 2010»
13 years 7 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
14 years 1 months ago
A Parallel Algorithm for Clustering Protein-Protein Interaction Networks
The increasing availability of interaction graphs requires new resource-efficient tools capable of extracting valuable biological knowledge from these networks. In this paper we ...
Qiaofeng Yang, Stefano Lonardi
VLDB
2002
ACM
83views Database» more  VLDB 2002»
13 years 7 months ago
Searching on the Secondary Structure of Protein Sequences
In spite of the many decades of progress in database research, surprisingly scientists in the life sciences community still struggle with inefficient and awkward tools for queryin...
Laurie Hammel, Jignesh M. Patel
NAR
2011
257views Computer Vision» more  NAR 2011»
12 years 10 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...