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» QTLminer: identifying genes regulating quantitative traits
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BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
Statistical significance of quantitative PCR
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
Yann Karlen, Alan McNair, Sébastien Persegu...
BMCBI
2004
115views more  BMCBI 2004»
13 years 7 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
BIOINFORMATICS
2008
203views more  BIOINFORMATICS 2008»
13 years 7 months ago
The SGN comparative map viewer
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
NAR
2008
113views more  NAR 2008»
13 years 7 months ago
miRNAMap 2.0: genomic maps of microRNAs in metazoan genomes
MicroRNAs (miRNAs) are small non-coding RNA molecules that can negatively regulate gene expression and thus control numerous cellular mechanisms. This work develops a resource, mi...
Sheng-Da Hsu, Chia-Huei Chu, Ann-Ping Tsou, Shu-Je...
GECCO
2009
Springer
14 years 2 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler