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» Quality Assessment of Peptide Tandem Mass Spectra
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IMSCCS
2006
IEEE
14 years 1 months ago
Quality Assessment of Peptide Tandem Mass Spectra
Background: Tandem mass spectrometry has emerged as a cornerstone of high throughput proteomic studies owing in part to various high throughput search engines which are used to in...
Fang-Xiang Wu, Pierre Gagné, Arnaud Droit, ...
BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
A Dynamic Noise Level Algorithm for Spectral Screening of Peptide MS/MS Spectra
Background: High-throughput shotgun proteomics data contain a significant number of spectra from non-peptide ions or spectra of too poor quality to obtain highly confident peptide...
Hua Xu, Michael A. Freitas
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
RECOMB
2003
Springer
14 years 7 months ago
On de novo interpretation of tandem mass spectra for peptide identification
The correct interpretation of tandem mass spectra is a difficult problem, even when it is limited to scoring peptides against a database. De novo sequencing is considerably harder...
Vineet Bafna, Nathan Edwards
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Peptide Charge State Determination for Low-Resolution Tandem Mass Spectra
Mass spectrometry is a particularly useful technology for the rapid and robust identification of peptides and proteins in complex mixtures. Peptide sequences can be identified b...
Aaron A. Klammer, Christine C. Wu, Michael J. MacC...