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» Quality Assessment of Peptide Tandem Mass Spectra
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DILS
2007
Springer
13 years 9 months ago
A High-Throughput Bioinformatics Platform for Mass Spectrometry-Based Proteomics
The success of mass spectrometry-based proteomics in emerging applications such as biomarker discovery and clinical diagnostics, is predicated substantially on its ability to achie...
Thodoros Topaloglou, Moyez Dharsee, Rob M. Ewing, ...
BMCBI
2008
119views more  BMCBI 2008»
13 years 7 months ago
Integrated multi-level quality control for proteomic profiling studies using mass spectrometry
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
David A. Cairns, David N. Perkins, Anthea J. Stanl...
BMCBI
2010
140views more  BMCBI 2010»
13 years 4 months ago
An improved machine learning protocol for the identification of correct Sequest search results
Background: Mass spectrometry has become a standard method by which the proteomic profile of cell or tissue samples is characterized. To fully take advantage of tandem mass spectr...
Morten Kallberg, Hui Lu
BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
Comparison of normalisation methods for surface-enhanced laser desorption and ionisation (SELDI) time-of-flight (TOF) mass spect
Background: Mass spectrometry for biological data analysis is an active field of research, providing an efficient way of high-throughput proteome screening. A popular variant of m...
Wouter Meuleman, Judith Y. M. N. Engwegen, Marie-C...
BMCBI
2008
184views more  BMCBI 2008»
13 years 7 months ago
"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI
Background: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecule...
Pornpat Nikamanon, Elroy Pun, Wayne Chou, Marek D....