During recent years there has been an explosive growth of biological data coming from genome projects, proteomics, protein structure determination, and the rapid expansion in digi...
Nasreddine Hireche, J. M. Pierre Langlois, Gabriel...
Homologousproteins do not necessarily exhibit identical biochemicalfunction. Despitethis fact, local or global sequence similarity is widely used as an indication of functional id...
— Data mining in biological structure libraries can be a powerful tool to better understand biochemical processes. This article introduces the LISA algorithm which enables the re...
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...