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BMCBI
2010
106views more  BMCBI 2010»
13 years 7 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
permGPU: Using graphics processing units in RNA microarray association studies
Background: Many analyses of microarray association studies involve permutation, bootstrap resampling and crossvalidation, that are ideally formulated as embarrassingly parallel c...
Ivo D. Shterev, Sin-Ho Jung, Stephen L. George, Ko...
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2010
74views more  BMCBI 2010»
13 years 7 months ago
Correcting for the effects of natural abundance in stable isotope resolved metabolomics experiments involving ultra-high resolut
Background: Stable isotope tracing with ultra-high resolution Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS) can provide simultaneous determination of hun...
Hunter N. B. Moseley
BMCBI
2007
145views more  BMCBI 2007»
13 years 7 months ago
Colony size measurement of the yeast gene deletion strains for functional genomics
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...
Negar Memarian, Matthew Jessulat, Javad Alirezaie,...