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BMCBI
2010
116views more  BMCBI 2010»
13 years 10 months ago
SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments
Background: High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these ...
David B. Burdick, Christopher C. Cavnor, Jeremy Ha...
BMCBI
2010
112views more  BMCBI 2010»
13 years 10 months ago
SeqAnt: A web service to rapidly identify and annotate DNA sequence variations
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
Amol Carl Shetty, Prashanth Athri, Kajari Mondal, ...
BMCBI
2007
135views more  BMCBI 2007»
13 years 10 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
BMCBI
2010
132views more  BMCBI 2010»
13 years 10 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
BMCBI
2008
173views more  BMCBI 2008»
13 years 10 months ago
Improved machine learning method for analysis of gas phase chemistry of peptides
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
Allison Gehrke, Shaojun Sun, Lukasz A. Kurgan, Nat...
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