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BIOINFORMATICS
2011
12 years 10 months ago
ProDy: Protein Dynamics Inferred from Theory and Experiments
Summary: We developed a Python package, ProDy, for structurebased analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heteroge...
Ahmet Bakan, Lidio M. Meireles, Ivet Bahar
BMCBI
2008
164views more  BMCBI 2008»
13 years 6 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2010
154views more  BMCBI 2010»
13 years 6 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2004
196views more  BMCBI 2004»
13 years 6 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2010
139views more  BMCBI 2010»
13 years 6 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...