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BMCBI
2008
109views more  BMCBI 2008»
13 years 7 months ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
WABI
2007
Springer
133views Bioinformatics» more  WABI 2007»
14 years 1 months ago
RNA Folding Including Pseudoknots: A New Parameterized Algorithm and Improved Upper Bound
Predicting the secondary structure of an RNA sequence is an important problem in structural bioinformatics. The general RNA folding problem, where the sequence to be folded may con...
Chunmei Liu, Yinglei Song, Louis W. Shapiro
CCECE
2006
IEEE
14 years 1 months ago
Evaluation of RNA Secondary Structure Motifs using Regression Analysis
Recent experimental evidences have shown that ribonucleic acid (RNA) plays a greater role in the cell than previously thought. An ensemble of RNA sequences believed to contain sig...
Mohammad Anwar, Marcel Turcotte
JCB
2007
136views more  JCB 2007»
13 years 7 months ago
A Structure-Based Flexible Search Method for Motifs in RNA
The discovery of non-coding RNA (ncRNA) motifs and their role in regulating gene expression has recently attracted considerable attention. The goal is to discover these motifs in ...
Isana Veksler-Lublinsky, Michal Ziv-Ukelson, Danny...
BMCBI
2007
183views more  BMCBI 2007»
13 years 7 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...