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» RNA Secondary Structure Prediction with Simple Pseudoknots
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BMCBI
2007
139views more  BMCBI 2007»
13 years 7 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
BMCBI
2008
137views more  BMCBI 2008»
13 years 7 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
DNA
2007
Springer
107views Bioinformatics» more  DNA 2007»
14 years 1 months ago
Autonomous Programmable Nanorobotic Devices Using DNAzymes
Abstract. A major challenge in nanoscience is the design of synthetic molecular devices that run autonomously and are programmable. DNA-based synthetic molecular devices have the a...
John H. Reif, Sudheer Sahu
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
RDMAS: a web server for RNA deleterious mutation analysis
Background: The diverse functions of ncRNAs critically depend on their structures. Mutations in ncRNAs disrupting the structures of functional sites are expected to be deleterious...
Wenjie Shu, Xiaochen Bo, Rujia Liu, Dongsheng Zhao...