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BMCBI
2004
133views more  BMCBI 2004»
13 years 10 months ago
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
Robin D. Dowell, Sean R. Eddy
BMCBI
2006
121views more  BMCBI 2006»
13 years 11 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
BMCBI
2004
116views more  BMCBI 2004»
13 years 10 months ago
Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure p
Background: A detailed understanding of an RNA's correct secondary and tertiary structure is crucial to understanding its function and mechanism in the cell. Free energy mini...
Kishore J. Doshi, Jamie J. Cannone, Christian W. C...
BMCBI
2006
158views more  BMCBI 2006»
13 years 11 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
APBC
2004
173views Bioinformatics» more  APBC 2004»
14 years 8 days ago
RNA Secondary Structure Prediction with Simple Pseudoknots
Pseudoknots are widely occurring structural motifs in RNA. Pseudoknots have been shown to be functionally important in different RNAs which play regulatory, catalytic, or structur...
Jitender S. Deogun, Ruben Donts, Olga Komina, Fang...