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BMCBI
2008
171views more  BMCBI 2008»
13 years 7 months ago
A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more
Background: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables ...
Harri T. Kiiveri
BMCBI
2006
110views more  BMCBI 2006»
13 years 7 months ago
Bias in error estimation when using cross-validation for model selection
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
Sudhir Varma, Richard Simon
BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2007
178views more  BMCBI 2007»
13 years 7 months ago
SVM clustering
Background: Support Vector Machines (SVMs) provide a powerful method for classification (supervised learning). Use of SVMs for clustering (unsupervised learning) is now being cons...
Stephen Winters-Hilt, Sam Merat
JMLR
2008
150views more  JMLR 2008»
13 years 7 months ago
Discriminative Learning of Max-Sum Classifiers
The max-sum classifier predicts n-tuple of labels from n-tuple of observable variables by maximizing a sum of quality functions defined over neighbouring pairs of labels and obser...
Vojtech Franc, Bogdan Savchynskyy