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BMCBI
2005
86views more  BMCBI 2005»
13 years 7 months ago
WebArray: an online platform for microarray data analysis
Background: Many cutting-edge microarray analysis tools and algorithms, including commonly used limma and affy packages in Bioconductor, need sophisticated knowledge of mathematic...
Xiaoqin Xia, Michael McClelland, Yipeng Wang
BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Significance analysis of microarray for relative quantitation of LC/MS data in proteomics
Background: Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positiv...
Bryan A. P. Roxas, Qingbo Li
BMCBI
2010
81views more  BMCBI 2010»
13 years 7 months ago
Empirical Bayes Analysis of Sequencing-based Transcriptional Profiling without Replicates
Background: Recent technological advancements have made high throughput sequencing an increasingly popular approach for transcriptome analysis. Advantages of sequencing-based tran...
Zhijin Wu, Bethany D. Jenkins, Tatiana A. Rynearso...
BMCBI
2004
111views more  BMCBI 2004»
13 years 7 months ago
Multiclass discovery in array data
Background: A routine goal in the analysis of microarray data is to identify genes with expression levels that correlate with known classes of experiments. In a growing number of ...
Yingchun Liu, Markus Ringnér
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Effects of dependence in high-dimensional multiple testing problems
Background: We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR) contro...
Kyung In Kim, Mark A. van de Wiel