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BMCBI
2008
219views more  BMCBI 2008»
13 years 9 months ago
Classification of premalignant pancreatic cancer mass-spectrometry data using decision tree ensembles
Background: Pancreatic cancer is the fourth leading cause of cancer death in the United States. Consequently, identification of clinically relevant biomarkers for the early detect...
Guangtao Ge, G. William Wong
BMCBI
2007
129views more  BMCBI 2007»
13 years 9 months ago
Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping
Background: The Sulston score is a well-established, though approximate metric for probabilistically evaluating postulated clone overlaps in DNA fingerprint mapping. It is known t...
Michael C. Wendl
BMCBI
2007
146views more  BMCBI 2007»
13 years 9 months ago
PubMed related articles: a probabilistic topic-based model for content similarity
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...
Jimmy J. Lin, W. John Wilbur
BMCBI
2006
81views more  BMCBI 2006»
13 years 9 months ago
Multipolar representation of protein structure
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Apostol Gramada, Philip E. Bourne
BMCBI
2007
145views more  BMCBI 2007»
13 years 9 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...