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» Reaction Motifs in Metabolic Networks
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WABI
2005
Springer
14 years 4 months ago
Reaction Motifs in Metabolic Networks
Vincent Lacroix, Cristina G. Fernandes, Marie-Fran...
BMCBI
2006
118views more  BMCBI 2006»
13 years 11 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
14 years 4 months ago
A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints
A linear programming algorithm is presented to constructively compute thermodynamically feasible fluxes and change in chemical potentials of reactions for a metabolic network. It...
R. Nigam, S. Liang
BMCBI
2010
133views more  BMCBI 2010»
13 years 11 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2010
86views more  BMCBI 2010»
13 years 11 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...