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» Reasoning from Data Rather than Theory
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CPM
2000
Springer
141views Combinatorics» more  CPM 2000»
13 years 11 months ago
A Lower Bound for the Breakpoint Phylogeny Problem
Breakpoint phylogenies methods have been shown to be an effective way to extract phylogenetic information from gene order data. Currently, the only practical breakpoint phylogeny a...
David Bryant
RECOMB
2004
Springer
14 years 8 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
ICDE
2010
IEEE
379views Database» more  ICDE 2010»
14 years 7 months ago
Osprey: Implementing MapReduce-Style Fault Tolerance in a Shared-Nothing Distributed Database
In this paper, we describe a scheme for tolerating and recovering from mid-query faults in a distributed shared nothing database. Rather than aborting and restarting queries, our s...
Christopher Yang, Christine Yen, Ceryen Tan, Samue...
BMCBI
2006
114views more  BMCBI 2006»
13 years 7 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2011
12 years 11 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...